Emergence of Escherichia coli ST131 sub-clone H30 producing VIM-1 and KPC-3 carbapenemases, Italy

Emergence of Escherichia coli ST131 sub-clone H30 producing VIM-1 and KPC-3 carbapenemases, Italy.

clone over years, even though repeated introductions of mecC-positive isolates cannot be excluded. Finally, the description of divergent but closely related spa types and PFGE patterns among the mecC-positive isolates potentially reflects local microevolution or the circulation of different subclones. No epidemiological link was evidenced between the three colonized farms, neither at the animal...

Emergence of a multiresistant KPC-3 and VIM-1 carbapenemase-producing Escherichia coli strain in Spain.

OBJECTIVES To characterize the mechanisms involved in carbapenem resistance, as well as the genetic elements supporting their mobilization, in a multidrug-resistant Escherichia coli isolate. METHODS The E. coli isolate was obtained from a patient with fatal urinary sepsis. Antimicrobial susceptibility testing was performed by the disc diffusion and agar dilution methods. The E. coli molecular...

Intercontinental emergence of Escherichia coli clone O25:H4-ST131 producing CTX-M-15.

BACKGROUND Concomitant with the recent emergence of CTX-M-type extended-spectrum beta-lactamases (ESBLs), Escherichia coli has become the enterobacterial species most affected by ESBLs. Multiple locales are encountering CTX-M-positive E. coli, including specifically CTX-M-15. To gain insights into the mechanism underlying this phenomenon, we assessed clonality and diversity of virulence profile...

Recurrent detection of VIM-1-producing Escherichia coli clone in German pig production

Emergence of Klebsiella pneumoniae Coharboring KPC and VIM Carbapenemases in Colombia.

Klebsiella pneumoniae strains coharboring KPC and VIM carbapenemases have been reported, to the best of our knowledge, only in Greece (1–5) and Germany (6). The coexpression of these two resistance determinants poses a major threat to antibiotic utility worldwide. Herein we report, for the first time in the Americas, a K. pneumoniae isolate harboring blaKPC and blaVIM genes. In September 2010, ...